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KMID : 1037820140030010014
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Journal of Pain and Autonomic Disorders
2014 Volume.3 No. 1 p.14 ~ p.21
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Mechanisms and Treatment Approaches of Phantom Limb Pain
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Lee Dong-Kuck
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Abstract
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Phantom limb pain(PLP) is a condition in which patients experience sensations, whether painful or otherwise, in a limb that dose not exist. PLP is a common sequela of amputation, occurring in up to 80% of people who undergo the procedure. It must be differentiated from non-painful phantom phenomena, residual-limb pain, and non-painful residual-limb phenomena. It typically has a chronic course, often resistant to treatment. Risk factors include the presence of preoperative pain, traumatic amputation, and the type of anesthetic procedure used during amputation. Several pathophysiologic theories have been proposed, including central sensitization, spinal mechanisms, and somatosensory cortical rearrangements, and while recent studies have shed light on some interesting and significant data, a lot remains to be understood. Treatments include pharmacotherapy, surgical/invasive procedures, and adjuvant therapy, but substantial efficacy in well-designed, randomized controlled trials has yet to be both understand and treat.
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KEYWORD
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Phantom limb pain, Mechanisms, Treatment
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